The long arm of childhood intelligence on terminal decline: Evidence from the Lothian Birth Cohort 1921.

ABSTRACT: The current study investigates the heterogeneity of cognitive trajectories at the end of life by assigning individuals into groups according to their cognitive trajectories prior to death. It also examines the role of childhood intelligence and education on these trajectories and group membership. Participants were drawn from the Lothian Birth Cohort of 1921 (LBC1921), a longitudinal study of individuals with a mean age of 79 years at study entry, and observed up to a maximum of five times to their early 90s. Growth mixture modeling was employed to identify groups of individuals with similar trajectories of global cognitive function measured with the Mini-Mental State Examination (MMSE) in relation to time to death, accounting for childhood intelligence, education, the time to death from s

SUBMITTER: Cadar D 

PROVIDER: S-EPMC8352070 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature