Temporal Associations and Outcomes of Breast Cancer and Heart Failure in Postmenopausal Women.

ABSTRACT:

Background

Heart failure (HF) and breast cancer are 2 of the leading causes of death in postmenopausal women. The temporal association between HF and breast cancer in postmenopausal women has not been described.

Objectives

This study sought to examine the temporal association between HF and breast cancer.

Methods

Postmenopausal women within the WHI (Women's Health Initiative) cohort were studied. All prevalent HF and prevalent breast cancer at enrollment were self-reported. Incident hospitalized HF and breast cancer diagnoses were adjudicated through 2017.

Results

Among a cohort of 44,174 women (mean age 63 ± 7 years), 2,188 developed incident invasive breast cancer and 2,416 developed incident hospitalized HF over a median follow-up of 14 and 15 years, respect

SUBMITTER: Lam PH 

PROVIDER: S-EPMC8352239 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature