Identification and genome analysis of Comamonas testosteroni strain JLU460ET, a novel steroid-degrading bacterium.

ABSTRACT: In this work, C. testosteroni JLU460ET isolated from animal waste was confirmed to have great degradation capability for 17β-estradiol and testosterone. This bacterium could degrade nearly 90% of 17β-estradiol (5 mg L^-1) in 4 days and transform it into estrone for further degradation. One hundred percent testosterone (144 mg L^-1) could be completely degraded after 9 h of incubation. This is the first report of C. testosteroni strains with the ability to degrade both estrogens and testosterone. The whole genome sequence of C. testosteroni JLU460ET was obtained and annotated, containing one chromosome (5,497,097 bp) with 61.37% GC content. A total of 4805 protein-coding genes and 134 RNA genes (including 29 rRNA genes, 102 tRNA genes and three ncRNA

SUBMITTER: Liu N 

PROVIDER: S-EPMC8353041 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature