Age Influences the Prognosis of Anaplastic Thyroid Cancer Patients.

ABSTRACT:

Background

The staging system for patients with anaplastic thyroid cancer (ATC) was updated in the 8^th edition of the American Joint Committee on Cancer Staging Manual. A cut-off age of 55 years was stipulated as a prognostic factor for differentiated thyroid cancer; however, age was not considered for ATC patients. To this end, this study investigated the relationship between age at diagnosis and prognosis of ATC patients.

Methods

The clinical information on ATC patients was acquired from the Surveillance, Epidemiology, and End Results Program public database. Youden's index and X-tile analyses were used to calculate the high-point age at diagnosis associated with prognosis. Cox proportional hazards models, Kaplan-Meier curves, and 1000-person-year were then used

SUBMITTER: Kong N 

PROVIDER: S-EPMC8353231 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature