ALKBH10B, an mRNA m⁶A Demethylase, Modulates ABA Response During Seed Germination in Arabidopsis.

ABSTRACT: As the most abundant and reversible chemical modification in eukaryotic mRNA, the epitranscriptomic mark N ⁶-methyladenine (m⁶A) regulates plant development and stress response. We have previously characterized that ALKBH10B is an Arabidopsis mRNA m⁶A demethylase and regulates floral transition. However, it is unclear whether ALKBH10B plays a role in abiotic stress response. Here, we found that the expression of ALKBH10B is increased in response to abscisic acid (ABA), osmotic, and salt stress. The alkbh10b mutants showed hypersensitive to ABA, osmotic, and salt stress during seed germination. Transcriptome analysis revealed that the expression of several ABA response genes is upregulated in alkbh10b-1 than that of wild type, ind

SUBMITTER: Tang J 

PROVIDER: S-EPMC8353332 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature