Understanding the Progression from Early Alcohol Use Experimentation to Alcohol Use Disorder: Testing Vulnerability by Experience Interactions Using a Two-Part Latent Growth Curve Model.

ABSTRACT: Most adolescents experiment with alcohol, but a smaller percentage advance to heavy alcohol use (AU) and AU disorder (AUD). Understanding for whom and how early risk leads to AUD is of interest to prevention, treatment, and etiology of AUD. Informed by developmental and behavioral neuroscience theory, the current study tested whether temperament (effortful control, surgency, and negative affect), peer AU (multi-reporter), and AU with parents' permission interacted to distinguish youth who experiment with alcohol from those who escalate to AUD. Community adolescents (N = 765, 53% female) were assessed annually for seven years (M_age = 11.8, range: 10-13 at Year 1; M_age = 18.7; range = 17-20 at year 7). Temperament by early experience interactions were expected to predic

SUBMITTER: Scalco MD 

PROVIDER: S-EPMC8353514 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature