Sex differences between serum total bilirubin levels and cognition in patients with schizophrenia.

ABSTRACT:

Background

Cognitive deficits are common in patients with schizophrenia (SCZ). Abnormal serum total bilirubin (TBIL) levels have been involved in cognitive deficits associated with neuropsychiatric diseases such as mild cognitive impairment and subcortical ischemic vascular disease. However, this relationship has not yet been fully investigated in patients with SCZ. Therefore, the aim of this study was to investigate the association between the serum TBIL concentration and cognitive deficits in SCZ patients and to determine whether a sex difference exists in the association.

Methods

A total of 455 participants were eligible and included in this cross-sectional study. Cognition was evaluated using the Montreal Cognitive Assessment. Serum TBIL concentration was measured with a

SUBMITTER: He S 

PROVIDER: S-EPMC8353745 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature