Recombinant human plasma gelsolin (rhu-pGSN) in a patient hospitalized with critical COVID-19 pneumonia.
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ABSTRACT:
SUBMITTER: Catteeuw JV
PROVIDER: S-EPMC8353968 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
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Recombinant human plasma gelsolin (rhu-pGSN) in a patient hospitalized with critical COVID-19 pneumonia.
Catteeuw Julie V JV DiNubile Mark J MJ
Clinical infection in practice 20210810
Life-threatening COVID-19 pneumonia follows an exaggerated immune response to SARS-CoV-2. pGSN levels fall after SARS-CoV-2 infection. Rhu-pGSN improves outcomes in models of inflammation. In an intubated patient with critical COVID-19 pneumonia and progressive hypoxemia despite standard care, improvement became evident during rhu-pGSN infusions with full recovery within a few weeks. ...[more]
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