Micro-computed tomography utility for estimation of intraparenchymal spinal cord cystic lesions in small animals.

ABSTRACT: Precise assessment of spinal cord cystic lesions is crucial to formulate effective therapeutic strategies, yet histological assessment of the lesion remains the primary method despite numerous studies showing inconsistent results regarding estimation of lesion size via histology. On the other hand, despite numerous advances in micro-computed tomography (micro-CT) imaging and analysis that have allowed precise measurements of lesion size, there is not enough published data on its application to estimate intraspinal lesion size in laboratory animal models. This work attempts to show that micro-CT can be valuable for spinal cord injury research by demonstrating accurate estimation of syrinx size and compares between micro-CT and traditional histological analysis. We used a post-traumatic syri

SUBMITTER: Farrag M 

PROVIDER: S-EPMC8354136 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature