Association Between Clinical Value and Financial Cost of Cancer Treatments: A Cross-Sectional Analysis.

ABSTRACT:

Background

The cost of cancer treatment has increased significantly in recent decades, but it is unclear whether these costs have been associated with commensurate improvement in clinical value. This study aimed to assess the association between the cost of cancer treatment and 4 of the 5 NCCN Evidence Blocks (EB) measures of clinical value: efficacy of regimen/agent, safety of regimen/agent, quality of evidence, and consistency of evidence.

Methods

This is a cross-sectional, observational study. We obtained NCCN EB ratings for all recommended, first-line, and/or maintenance treatments for the 30 most prevalent cancers in the United States and calculated direct pharmacologic treatment costs (drug acquisition, administration fees, guideline-concordant supportive care medicati

SUBMITTER: Mitchell AP 

PROVIDER: S-EPMC8354655 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature