Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21 773 Brazilian adult and elderly inpatients.

ABSTRACT:

Objectives

To investigate the combined association of obesity, diabetes mellitus (DM) and cardiovascular disease (CVD) with severe COVID-19 outcomes in adult and elderly inpatients.

Design

Cross-sectional study based on registry data from Brazil's influenza surveillance system.

Setting

Public and private hospitals across Brazil.

Participants

Eligible population included 21 942 inpatients aged ≥20 years with positive reverse transcription-PCR test for SARS-CoV-2 until 9 June 2020.

Main outcome measures

Severe COVID-19 outcomes were non-invasive and invasive mechanical ventilation use, intensive care unit (ICU) admission and death. Multivariate analyses were conducted separately for adults (20-59 years) and elders (≥60 years) to test the combined associati

SUBMITTER: Silva NJ 

PROVIDER: S-EPMC8354760 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature