Analysis of Turbulence Effects in a Patient-Specific Aorta with Aortic Valve Stenosis.

ABSTRACT: Blood flow in the aorta is often assumed laminar, however aortic valve pathologies may induce transition to turbulence and our understanding of turbulence effects is incomplete. The aim of the study was to provide a detailed analysis of turbulence effects in aortic valve stenosis (AVS).

Methods

Large-eddy simulation (LES) of flow through a patient-specific aorta with AVS was conducted. Magnetic resonance imaging (MRI) was performed and used for geometric reconstruction and patient-specific boundary conditions. Computed velocity field was compared with 4D flow MRI to check qualitative and quantitative consistency. The effect of turbulence was evaluated in terms of fluctuating kinetic energy, turbulence-related wall shear stress (WSS) and energy loss.

Results

Our analysis sugge

SUBMITTER: Manchester EL 

PROVIDER: S-EPMC8354935 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature