Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis.

ABSTRACT:

Purpose

This review provides an updated overview of observational and intervention studies investigating the effect of a low-FODMAP (fermentable oligo-, di- and monosaccharides, and polyols) diet (LFD) on gastrointestinal (GI) symptoms, quality of life (QoL), nutritional adequacy, and gut microbiome in irritable bowel syndrome (IBS) patients.

Methods

We systematically searched available literature until October 2020 for studies that investigated the effect of LFDs on GI symptoms, QoL, nutritional adequacy, and the gut microbiome in IBS patients. The data were represented as standardized mean differences (SMD) for IBS severity, and as mean differences (MD) for IBS-QoL. Meta-analyses were performed for the quantitative analyses using random effects models with inverse variance

SUBMITTER: van Lanen AS 

PROVIDER: S-EPMC8354978 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature