Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles.

ABSTRACT: In humans and other mammals, the stillness of sleep is punctuated by bursts of rapid eye movements (REMs) and myoclonic twitches of the limbs.¹ Like the spontaneous activity that arises from the sensory periphery in other modalities (e.g., retinal waves),² sensory feedback arising from twitches is well suited to drive activity-dependent development of the sensorimotor system.³ It is partly because of the behavioral activation of REM sleep that this state is also called active sleep (AS), in contrast with the behavioral quiescence that gives quiet sleep (QS)-the second major stage of sleep-its name. In human infants, for which AS occupies 8 h of each day,⁴ twitching helps to identify the state;^5-8 nonetheless, we know little about the s

SUBMITTER: Sokoloff G 

PROVIDER: S-EPMC8355086 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature