Activation of Person Knowledge in Medial Prefrontal Cortex during the Encoding of New Lifelike Events.

ABSTRACT: Our knowledge about people can help us predict how they will behave in particular situations and interpret their actions. In this study, we investigated the cognitive and neural effects of person knowledge on the encoding and retrieval of novel life-like events. Healthy human participants learnt about two characters over a week by watching 6 episodes of one of two situation comedies, which were both centered on a young couple. In the scanner, they watched and then silently recalled 20 new scenes from both shows that were all set in unfamiliar locations: 10 from their trained show and 10 from the untrained show. After scanning, participants' recognition memory was better for scenes from the trained show. The functional magnetic resonance imaging (fMRI) patterns of brain activity when watchi

SUBMITTER: Raykov PP 

PROVIDER: S-EPMC8355471 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature