A meta-analysis on the risk factors adjusted association between cardiovascular disease and COVID-19 severity.

ABSTRACT:

Background

Cardiovascular disease (CVD), one of the most common comorbidities of coronavirus disease 2019 (COVID-19), has been suspected to be associated with adverse outcomes in COVID-19 patients, but their correlation remains controversial.

Method

This is a quantitative meta-analysis on the basis of adjusted effect estimates. PubMed, Web of Science, MedRxiv, Scopus, Elsevier ScienceDirect, Cochrane Library and EMBASE were searched comprehensively to obtain a complete data source up to January 7, 2021. Pooled effects (hazard ratio (HR), odds ratio (OR)) and the 95% confidence intervals (CIs) were estimated to evaluate the risk of the adverse outcomes in COVID-19 patients with CVD. Heterogeneity was assessed by Cochran's Q-statistic, I²test, and meta-regression. I

SUBMITTER: Xu J 

PROVIDER: S-EPMC8355578 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature