Horizontal Transmission of the Symbiont Microsporidia MB in Anopheles arabiensis.

ABSTRACT: The recently discovered Anopheles symbiont, Microsporidia MB, has a strong malaria transmission-blocking phenotype in Anopheles arabiensis, the predominant Anopheles gambiae species complex member in many active transmission areas in eastern Africa. The ability of Microsporidia MB to block Plasmodium transmission together with vertical transmission and avirulence makes it a candidate for the development of a symbiont-based malaria transmission blocking strategy. We investigate the characteristics and efficiencies of Microsporidia MB transmission between An. arabiensis mosquitoes. We show that Microsporidia MB is not transmitted between larvae but is effectively transmitted horizontally between adult mosquitoes. Notably, Micr

SUBMITTER: Nattoh G 

PROVIDER: S-EPMC8355901 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature