Association of Diphtheria-Tetanus-Acellular Pertussis Vaccine Timeliness and Number of Doses With Age-Specific Pertussis Risk in Infants and Young Children.

ABSTRACT:

Importance

In most countries, the diphtheria-tetanus-acellular pertussis (DTaP) vaccine is administered as a 3-dose infant series followed by additional booster doses in the first 5 years of life. Short-term immunity from the DTaP vaccine can depend on the number, timing, and interval between doses. Not receiving doses in a timely manner might be associated with a higher pertussis risk.

Objective

To examine the association between number and timeliness of vaccine doses and age-specific pertussis risk.

Design, setting, and participants

This population-based, retrospective cohort study used Washington State Immunization Information System data and pertussis surveillance data from Public Health Seattle and King County, Washington. Included participants were children aged

SUBMITTER: Rane MS 

PROVIDER: S-EPMC8356064 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature