Epidemiology of herpes simplex virus type 2 in Asia: A systematic review, meta-analysis, and meta-regression.

ABSTRACT:

Background

Herpes simplex virus type 2 (HSV-2) infection is a prevalent sexually transmitted infection worldwide. This systematic review was conducted to characterize HSV-2 epidemiology in Asia, including the World Health Organization regions of Southeast Asia and the Western Pacific.

Methods

Cochrane and PRISMA guidelines were followed to systematically review and report findings. Pooled mean seroprevalence and proportions of HSV-2 isolated in genital ulcer disease (GUD) and in genital herpes were calculated using random-effects meta-analyses. Meta-regressions were also conducted. Quality assessment was performed.

Findings

HSV-2 measures extracted from 173 publications included 15 seroconversion rates, 11 seroincidence rates, 272 overall seroprevalence measures (678

SUBMITTER: AlMukdad S 

PROVIDER: S-EPMC8356094 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature