Tuberculosis care cascade in Zambia - identifying the gaps in order to improve outcomes: a population-based analysis.

ABSTRACT:

Objective

Tuberculosis (TB) remains a leading cause of morbidity and mortality in Zambia, especially for people living with HIV (PLHIV). We undertook a care cascade analysis to quantify gaps in care and align programme improvement measures with areas of need.

Design

Retrospective, population-based analysis.

Setting

We derived national-level estimates for each step of the TB care cascade in Zambia. Estimates were informed by WHO incidence estimates, nationally aggregated laboratory and notification registers, and individual-level programme data from four provinces.

Participants

Participants included all individuals with active TB disease in Zambia in 2018. We characterised the overall TB cascade and disaggregated by drug susceptibility results and HIV status.

SUBMITTER: Lungu P 

PROVIDER: S-EPMC8356169 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature