A Genome-Wide Analysis of Antibiotic Producing Genes in Streptomyces globisporus SP6C4.

ABSTRACT: Soil is the major source of plant-associated microbes. Several fungal and bacterial species live within plant tissues. Actinomycetes are well known for producing a variety of antibiotics, and they contribute to improving plant health. In our previous report, Streptomyces globisporus SP6C4 colonized plant tissues and was able to move to other tissues from the initially colonized ones. This strain has excellent antifungal and antibacterial activities and provides a suppressive effect upon various plant diseases. Here, we report the genome-wide analysis of antibiotic producing genes in S. globisporus SP6C4. A total of 15 secondary metabolite biosynthetic gene clusters were predicted using antiSMASH. We used the CRISPR/Cas9 mutagenesis system, and each biosynthetic gene was predicted via prote

SUBMITTER: Kim DR 

PROVIDER: S-EPMC8357572 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature