Diagnostic value of video-oculography in progressive supranuclear palsy: a controlled study in 100 patients.

ABSTRACT:

Background

The eponymous feature of progressive supranuclear palsy (PSP) is oculomotor impairment which is one of the relevant domains in the Movement Disorder Society diagnostic criteria.

Objective

We aimed to investigate the value of specific video-oculographic parameters for the use as diagnostic markers in PSP.

Methods

An analysis of video-oculography recordings of 100 PSP patients and 49 age-matched healthy control subjects was performed. Gain of smooth pursuit eye movement and latency, gain, peak eye velocity, asymmetry of downward and upward velocities of saccades as well as rate of saccadic intrusions were analyzed.

Results

Vertical saccade velocity and saccadic intrusions allowed for the classification of about 70% and 56% of the patients, respectively

SUBMITTER: Wunderlich J 

PROVIDER: S-EPMC8357639 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature