The impact of hyperbaric oxygen therapy on late radiation toxicity and quality of life in breast cancer patients.

ABSTRACT:

Purpose

To evaluate symptoms of late radiation toxicity, side effects, and quality of life in breast cancer patients treated with hyperbaric oxygen therapy (HBOT).

Methods

For this cohort study breast cancer patients treated with HBOT in 5 Dutch facilities were eligible for inclusion. Breast cancer patients with late radiation toxicity treated with ≥ 20 HBOT sessions from 2015 to 2019 were included. Breast and arm symptoms, pain, and quality of life were assessed by means of the EORTC QLQ-C30 and -BR23 before, immediately after, and 3 months after HBOT on a scale of 0-100. Determinants associated with persistent breast pain after HBOT were assessed.

Results

1005/1280 patients were included for analysis. Pain scores decreased significantly from 43.4 before HBOT to 29.7

SUBMITTER: Batenburg MCT 

PROVIDER: S-EPMC8357739 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature