"Omics" in traumatic brain injury: novel approaches to a complex disease.

ABSTRACT:

Background

To date, there is neither any pharmacological treatment with efficacy in traumatic brain injury (TBI) nor any method to halt the disease progress. This is due to an incomplete understanding of the vast complexity of the biological cascades and failure to appreciate the diversity of secondary injury mechanisms in TBI. In recent years, techniques for high-throughput characterization and quantification of biological molecules that include genomics, proteomics, and metabolomics have evolved and referred to as omics.

Methods

In this narrative review, we highlight how omics technology can be applied to potentiate diagnostics and prognostication as well as to advance our understanding of injury mechanisms in TBI.

Results

The omics platforms provide possibilities t

SUBMITTER: Abu Hamdeh S 

PROVIDER: S-EPMC8357753 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature