Delta band activity contributes to the identification of command following in disorder of consciousness.

ABSTRACT: The overt or covert ability to follow commands in patients with disorders of consciousness is considered a sign of awareness and has recently been defined as cortically mediated behaviour. Despite its clinical relevance, the brain signatures of the perceptual processing supporting command following have been elusive. This multimodal study investigates the temporal spectral pattern of electrical brain activity to identify features that differentiated healthy controls from patients both able and unable to follow commands. We combined evidence from behavioural assessment, functional neuroimaging during mental imagery and high-density electroencephalography collected during auditory prediction, from 21 patients and 10 controls. We used a penalised regression model to identify command following

SUBMITTER: Rivera-Lillo G 

PROVIDER: S-EPMC8357781 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature