Risk Factors for Premature Myocardial Infarction: A Systematic Review and Meta-analysis of 77 Studies.

ABSTRACT:

Objective

To evaluate the magnitude of the association between risk factors and premature myocardial infarction (MI) (men aged 18-55 years; women aged 18-65 years).

Patients and methods

We searched MEDLINE and other databases from inception through April 30, 2020, as well as bibliography of articles selected for data extraction. We selected observational studies reporting the magnitude of the association of at least 1 risk factor (demographic characteristics, lifestyle factors, clinical risk factors, or biomarkers) with premature MI and a control group. Pooled risk estimates (random effects) from all studies unadjusted and adjusted for risk factors were reported as summary odds ratios (ORs) with 95% CIs.

Results

From 35,320 articles of 12.7 million participants, we ex

SUBMITTER: Dugani SB 

PROVIDER: S-EPMC8358212 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature