Evaluation of Early vs Standard Liver Transplant for Alcohol-Associated Liver Disease.

ABSTRACT:

Importance

Traditionally, liver transplant (LT) for alcohol-associated liver disease (ALD) requires 6 months of abstinence. Although early LT before 6 months of abstinence has been associated with decreased mortality for decompensated ALD, this practice remains controversial and concentrated at a few centers.

Objective

To define patient, allograft, and relapse-free survival in early LT for ALD, and to investigate the association between these survival outcomes and early vs standard LT.

Design, setting, and participants

This cohort study analyzed all patients with ALD who underwent their first LT at a single academic referral center between October 1, 2012, and November 13, 2020. Patients with known pretransplant hepatocellular carcinoma, hepatitis B or C, or an altern

SUBMITTER: Herrick-Reynolds KM 

PROVIDER: S-EPMC8358815 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature