Fabrication of Zwitterion TiO₂ Nanomaterial-Based Nanocomposite Membranes for Improved Antifouling and Antibacterial Properties and Hemocompatibility and Reduced Cytotoxicity.

ABSTRACT: Although zwitterion nanomaterials exhibit outstanding antifouling property, hemocompatibility, and antibacterial activity, their poor solubility in organic solvents limits their practical applications. In the present study, natural lysine (amino acids) was surface-grafted onto one-dimensional (1D) TiO₂ nanofibers (NFs) through an epoxy ring opening in which the 3-glycidyloxypropyl (dimethoxy) methyl silane was used as a coupling agent. Chemical binding and morphological studies, such as Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and transmission electron microscopy, were conducted to confirm the successful grafting of lysine onto the TiO₂ NFs. The lysine-grafted TiO₂ NF-polyethersulfone (PES) membrane induced electrostatic in

SUBMITTER: Venkatesh K 

PROVIDER: S-EPMC8358967 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature