Uptake of fetal aneuploidy screening after the introduction of the non-invasive prenatal test: A national population-based register study.

ABSTRACT:

Introduction

The introduction of the non-invasive prenatal test (NIPT) has shifted the prenatal screening landscape. Countries are exploring ways to integrate NIPT in their national prenatal screening programs, either as a first- or second-tier test. This study aimed to describe how the uptake of fetal aneuploidy screening changed after the introduction of NIPT as a second-tier and as a first-tier test within the national prenatal screening program of the Netherlands.

Material and methods

A population-based register study in the Netherlands, recording uptake of fetal aneuploidy screening. Data from all pregnant women choosing to have the first-trimester combined test (FCT) or first-tier NIPT between January 2007 and March 2019 were retrospectively collected using national re

SUBMITTER: van der Meij KRM 

PROVIDER: S-EPMC8359325 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature