Clinicopathological features and prognosis of patients with pregnancy-associated breast cancer: A matched case control study.

ABSTRACT:

Aim

We aimed to clarify tumor features and prognosis of pregnancy-associated breast cancer (PABC) among Chinese women.

Methods

PABC was defined as breast cancer diagnosed during pregnancy or within a year after delivery. Patients with PABC were selected from breast cancer cases of women ≤45 years treated at our institution between December 2012 and December 2017, and one non-PABC control was matched for stage, age, and year of diagnosis for each case.

Results

Forty-one women with PABC were identified (22 diagnosed during pregnancy and 19 within 1 year of delivery). There were significantly more progesterone receptor (PR)- and triple-negative tumors in the PABC (56.1% and 24.4%, respectively) than in the non-PABC group (31.7% and 4.9%, respectively) (P = .045 and .026,

SUBMITTER: Zhang R 

PROVIDER: S-EPMC8359456 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature