Fa(c)t checking: How fatty acids shape metabolism and function of macrophages and dendritic cells.
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ABSTRACT:
SUBMITTER: Almeida L
PROVIDER: S-EPMC8359938 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
Fa(c)t checking: How fatty acids shape metabolism and function of macrophages and dendritic cells.
European journal of immunology 20210419 7
In recent years there have been major advances in our understanding of the role of free fatty acids (FAs) and their metabolism in shaping the functional properties of macrophages and DCs. This review presents the most recent insights into how cell intrinsic FA metabolism controls DC and macrophage function, as well as the current evidence of the importance of various exogenous FAs (such as polyunsaturated FAs and their oxidation products-prostaglandins, leukotrienes, and proresolving lipid media ...[more]
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