Relationship Between Early Functional and Structural Brain Developments and Brain Injury in Preterm Infants.

ABSTRACT:

Background

Recent studies explored the relationship between early brain function and brain morphology, based on the hypothesis that increased brain activity can positively affect structural brain development and that excitatory neuronal activity stimulates myelination.

Objective

To investigate the relationship between maturational features from early and serial aEEGs after premature birth and MRI metrics characterizing structural brain development and injury, measured around 30weeks postmenstrual age (PMA) and at term. Moreover, we aimed to verify whether previously developed maturational EEG features are related with PMA.

Design/methods

One hundred six extremely preterm infants received bedside aEEGs during the first 72h and weekly until week 5. 3T-MRIs were performe

SUBMITTER: De Wel O 

PROVIDER: S-EPMC8360868 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature