Postmastectomy radiation therapy and survival outcome in older patients with T1-2N1 breast cancer.

ABSTRACT:

Background

The prognostic impact of postmastectomy radiation therapy (PMRT) on contemporary older patients with T1-2N1 breast cancer is unclear. We aimed to investigate the effect of PMRT in this setting.

Methods

Leveraging the Surveillance, Epidemiology, and End Results (SEER) program data from 2004 to 2015, 7052 patients aged 70 years or older with T1-2N1 breast cancer were identified for this propensity-matched analysis. Fine and Gray competing risks regression was conducted to explore the correlation between PMRT and breast cancer-specific survival, in subgroups defined by tumor size and positive lymph nodes.

Results

The median follow-up was 60.1 months (interquartile range, 28.0 to 87.0). Among propensity-matched patients, multivariate analysis identified an asso

SUBMITTER: Luo C 

PROVIDER: S-EPMC8361178 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature