Cryoanalgesia for postsurgical pain relief in adults: A systematic review and meta-analysis.

ABSTRACT:

Background

Despite advances in pain management, postoperative pain continues to be an important problem with significant burden. Many current therapies have dose-limiting adverse effects and are limited by their short duration of action. This review examines the evidence for the efficacy and safety of cryoanalgesia in postoperative pain.

Materials and methods

This review was registered in PROSPERO and prepared in accordance with PRISMA. MEDLINE, EMBASE, and Cochrane databases were searched until July 2020. We included randomized controlled trials (RCTs) of adults evaluating perioperatively administered cryoanalgesia for postoperative pain relief.

Results

Twenty-four RCTS were included. Twenty studies examined cryoanalgesia for thoracotomy, two for herniorrhaphy, one f

SUBMITTER: Park R 

PROVIDER: S-EPMC8361293 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature