Association Between Chemotherapy and Survival in T1 Colon Cancer With Lymph Node Metastasis: A Propensity-Score Matched Analysis.

ABSTRACT: This study aimed to comprehensively examine the efficacy of chemotherapy in T1 colon cancer patients with lymph node metastasis.

Methods

The differences in categorical variables in colon cancer patients according to lymph node status were evaluated by Pearson's chi-square test. The Kaplan-Meier method was used to assess Cancer-specific survival (CSS) and overall survival (OS) with the log-rank test. Cox proportional hazards models were built, multivariate Cox regression analyses were performed with the hazard ratio (HR) and 95% confidence interval (CI) to identify the potential independent prognostic factors. Propensity score matching was also undertaken to adjust for treatment bias due to measured confounders.

Results

Younger age (52.2% VS. 43.0% for ≤ 65 years old, p < 0.00

SUBMITTER: Yan W 

PROVIDER: S-EPMC8361445 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature