Detecting myasthenia gravis as a cause of unclear dysphagia with an endoscopic tensilon test.

ABSTRACT:

Aims

The flexible endoscopic evaluation of swallowing-tensilon test (FTT) was developed to diagnose myasthenia gravis (MG) in patients with unclear pharyngeal dysphagia. The purpose of this study was to determine sensitivity and specificity of the FTT and compare its diagnostic validity with that of other diagnostic markers.

Methods

In this single-centre pragmatic clinical cohort study, a total of 100 patients with unclear pharyngeal dysphagia were eligible to undergo FTT. All patients were subjected to FTT and subsequently followed up clinically. FTT was considered positive if a significant improvement of pharyngeal swallowing function could be objectified endoscopically upon administration of edrophonium chloride. In addition, repetitive nerve stimulation test and serum MG

SUBMITTER: Warnecke T 

PROVIDER: S-EPMC8361548 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature