Impact of antibiotic pretreatment on cultures in children with osteomyelitis and septic arthritis: a retrospective review.

ABSTRACT:

Background

In the management of pediatric osteomyelitis or septic arthritis, delay in treatment may affect outcome, while receipt of antibiotics prior to culture may affect culture results. We aimed to determine if pathogen identification decreased in cultures that were pretreated with antibiotics.

Methods

We conducted a retrospective cohort study of 584 hospitalized children between 30 days and 18 years of age admitted to two tertiary children's hospitals. Logistic regression assessed the effect of antibiotic duration on blood, bone, joint aspirate, and "other" culture positivity.

Results

Overall, 42% of blood cultures, 70% of bone cultures, 39% of joint cultures, and 70% of "other" cultures were positive. Compared with children who did not receive antibiotics prior

SUBMITTER: Lansell A 

PROVIDER: S-EPMC8361620 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature