Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience.

ABSTRACT:

Background

Disease resilience, which is the ability of an animal to maintain performance under disease, is important for pigs in commercial herds, where they are exposed to various pathogens. Our objective was to investigate population-level gene expression profiles in the blood of 912 healthy F1 barrows at ~ 27 days of age for associations with performance and health before and after their exposure to a natural polymicrobial disease challenge at ~ 43 days of age.

Results

Most significant (q < 0.20) associations of the level of expression of individual genes in blood of young healthy pigs were identified for concurrent growth rate and subjective health scores prior to the challenge, and for mortality, a combined mortality-treatment trait, and feed conversion rate after the c

SUBMITTER: Lim KS 

PROVIDER: S-EPMC8361860 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature