What to measure in biliary atresia research: study protocol for developing a core outcome set.

ABSTRACT:

Aim

Extrahepatic biliary atresia is a rare disorder. This creates challenges in the quality and quantity of research conducted. This issue is exacerbated by the potential heterogeneity in the reported outcomes in research examining the management of biliary atresia. A core outcome set is required to standardise reporting on the management of biliary atresia in research, facilitate systematic reviews that include outcomes of greatest importance to patients and clinicians, and to evaluate the quality of the existing evidence base on the management of biliary atresia.

Methods

A list of all potential outcomes will be developed through a systematic review of the literature. This list will be refined through a three-stage Delphi approach, involving key stakeholders in the manageme

SUBMITTER: Maguire C 

PROVIDER: S-EPMC8362727 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature