Lymphopenia in hospitalized patients and its relationship with severity of illness and mortality.

ABSTRACT:

Background

Lymphopenia is associated with various pathologies such as sepsis, burns, trauma, general anesthesia and major surgeries. All these pathologies are clinically expressed by the so-called Systemic Inflammatory Response Syndrome which does not include lymphopenia into defining criteria. The main objective of this work was to analyze the diagnosis of patients admitted to a hospital related to lymphopenia during hospital stay. In addition, we investigated the relationship of lymphopenia with the four levels of the Severity of Illness (SOI) and the Risk of Mortality (ROM).

Method and findings

Lymphopenia was defined as Absolute Lymphocyte Count (ALC) <1.0 x109/L. ALC were analyzed every day since admission. The four levels (minor, moderate, major and extreme risk) of bo

SUBMITTER: Andreu-Ballester JC 

PROVIDER: S-EPMC8362940 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature