Ontology highlight
ABSTRACT:
SUBMITTER: Moiseenko A
PROVIDER: S-EPMC8363050 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Moiseenko Alena A Vazquez-Armendariz Ana Ivonne AI Kheirollahi Vahid V Chu Xuran X Tata Aleksandra A Rivetti Stefano S Günther Stefan S Lebrigand Kevin K Herold Susanne S Braun Thomas T Mari Bernard B De Langhe Stijn S Kwapiszewska Grazyna G Günther Andreas A Chen Chengshui C Seeger Werner W Tata Purushothama Rao PR Zhang Jin-San JS Bellusci Saverio S El Agha Elie E
Cell reports 20201201 12
Tissue regeneration requires coordinated and dynamic remodeling of stem and progenitor cells and the surrounding niche. Although the plasticity of epithelial cells has been well explored in many tissues, the dynamic changes occurring in niche cells remain elusive. Here, we show that, during lung repair after naphthalene injury, a population of PDGFRα<sup>+</sup> cells emerges in the non-cartilaginous conducting airway niche, which is normally populated by airway smooth muscle cells (ASMCs). This ...[more]