Emergence of the First Strains of SARS-CoV-2 Lineage B.1.1.7 in Romania: Genomic Analysis.

ABSTRACT:

Background

The United Kingdom reported the emergence of a new and highly transmissible SARS-CoV-2 variant (B.1.1.7) that rapidly spread to other countries. The impact of this new mutation-which occurs in the S protein-on infectivity, virulence, and current vaccine effectiveness is still under evaluation.

Objective

The aim of this study is to sequence SARS-CoV-2 samples of cases in Romania to detect the B.1.1.7 variant and compare these samples with sequences submitted to GISAID.

Methods

SARS-CoV-2 samples were sequenced and amino acid substitution analysis was performed using the CoV-GLUE platform.

Results

We have identified the first cases of the B.1.1.7 variant in samples collected from Romanian patients, of which one was traced to the region of the United Ki

SUBMITTER: Lobiuc A 

PROVIDER: S-EPMC8363123 | biostudies-literature | 2021 Jul-Sep

REPOSITORIES: biostudies-literature