Evaluating Gait and Locomotion in Rodents with the CatWalk.

ABSTRACT: Motor deficits can significantly affect the completion of daily life activities and have a negative impact on quality of life. Consequently, motor function is an important behavioral endpoint to measure for in vivo pathophysiologic studies in a variety of research areas, such as toxicant exposure, drug development, disease characterization, and transgenic phenotyping. Evaluation of motor function is also critical to the interpretation of cognitive behavioral assays, as many rely on intact motor abilities to derive meaningful data. As such, gait analysis is an important component of behavioral research and can be achieved by manual or video-assisted methods. Manual gait analysis methods, however, are prone to observer bias and are unable to capture many critical parameters. In contrast, aut

SUBMITTER: Garrick JM 

PROVIDER: S-EPMC8363132 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature