Neonatal Brain Response to Deviant Auditory Stimuli and Relation to Maternal Trait Anxiety.

ABSTRACT:

Objective

Excessive response to unexpected or "deviant" stimuli during infancy and early childhood represents an early risk marker for anxiety disorders. However, research has yet to delineate the specific brain regions underlying the neonatal response to deviant stimuli near birth and the relation to risk for anxiety disorders. The authors used task-based functional MRI (fMRI) to delineate the neonatal response to deviant stimuli and its relationship to maternal trait anxiety.

Methods

The authors used fMRI to measure brain activity evoked by deviant auditory stimuli in 45 sleeping neonates (mean age, 27.8 days; 60% female; 64% African American). In 41 of the infants, neural response to deviant stimuli was examined in relation to maternal trait anxiety on the State-Trait Anx

SUBMITTER: Sylvester CM 

PROVIDER: S-EPMC8363512 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature