Facial analysis technology for the detection of Down syndrome in the Democratic Republic of the Congo.

ABSTRACT: Down syndrome is one of the most common chromosomal anomalies affecting the world's population, with an estimated frequency of 1 in 700 live births. Despite its relatively high prevalence, diagnostic rates based on clinical features have remained under 70% for most of the developed world and even lower in countries with limited resources. While genetic and cytogenetic confirmation greatly increases the diagnostic rate, such resources are often non-existent in many low- and middle-income countries, particularly in Sub-Saharan Africa. To address the needs of countries with limited resources, the implementation of mobile, user-friendly and affordable technologies that aid in diagnosis would greatly increase the odds of success for a child born with a genetic condition. Given that the Democrat

SUBMITTER: Porras AR 

PROVIDER: S-EPMC8363515 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature