Thrombotic activation before and after total hip arthroplasty. A prospective cohort study.

ABSTRACT:

Background

Total hip arthroplasty (THA) causes acute blood loss. It may lead to a deficiency in coagulation factors, which, in turn, may lead to increased bleeding during the postoperative period.

Methods

Thirty patients (18 women) with a mean age of 67 years (range: 63-72 years) participated in this prospective diagnostic study. THA was performed without tranexamic acid administration in the perioperative period. Activities of clotting factors II, VIII, X, and fibrinogen concentration were evaluated before surgery, 6 hours after the procedure, 2, 4, and 6 days after the operation. All laboratory tests were performed using ACL TOP 500 CTS analyzer.

Results

No thromboembolic complications were noted during hospitalization. Mean fibrinogen concentration was 366 mg/dL be

SUBMITTER: Burbul M 

PROVIDER: S-EPMC8364023 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature