Ontology highlight
ABSTRACT:
SUBMITTER: Davidson JL
PROVIDER: S-EPMC8364207 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Davidson Josiah Levi JL Wang Jiangshan J Maruthamuthu Murali Kannan MK Dextre Andres A Pascual-Garrigos Ana A Mohan Suraj S Putikam Sai Venkata Sravan SVS Osman Fujr Osman Ibrahim FOI McChesney Darby D Seville Jordan J Verma Mohit S MS
Biosensors & bioelectronics: X 20210814
Herein, we describe the development of a paper-based device to detect nucleic acids of pathogens of interest in complex samples using loop-mediated isothermal amplification (LAMP) by producing a colorimetric response visible to the human eye. To demonstrate the utility of this device in emerging public health emergencies, we developed and optimized our device to detect SARS-CoV-2 in human saliva without preprocessing. The resulting device was capable of detecting the virus within 60 min and had ...[more]