Light-induced, spatiotemporal control of protein in the developing embryo of the sea urchin.

ABSTRACT: Differential protein regulation is a critical biological process that regulates cellular activity and controls cell fate determination. It is especially important during early embryogenesis when post-transcriptional events predominate differential fate specification in many organisms. Light-induced approaches have been a powerful technology to interrogate protein functions with temporal and spatial precision, even at subcellular levels within a cell by controlling laser irradiation on the confocal microscope. However, application and efficacy of these tools need to be tested for each model system or for the cell type of interest because of the complex nature of each system. Here, we introduce two types of light-induced approaches to track and control proteins at a subcellular level in the

SUBMITTER: Wavreil FDM 

PROVIDER: S-EPMC8364515 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature