Peripheral artery disease and clinical outcomes in patients with atrial fibrillation: A systematic review and meta-analysis.

ABSTRACT:

Background

Atrial fibrillation (AF) is the most common cardiac rhythm disturbance and leads to morbidity and mortality. Peripheral artery disease (PAD) is associated with atherosclerotic risk factors and always classified as a vascular disease and deemed to be a bad complication of AF. In patients with AF, the risk and prognostic value of PAD have not been estimated comprehensively.

Hypothesis

PAD is associated with all-cause mortality, cardiovascular (CV) mortality, and other outcomes in patients with AF.

Methods

We searched PubMed, Embase, and Cochrane Library databases for prospective studies published before April 2021 that provided outcomes data on PAD in confirmed patients with AF. Heterogeneity was estimated using the I² statistic. The fixed-effects

SUBMITTER: Zhu J 

PROVIDER: S-EPMC8364730 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature