Clustering of blood cell count abnormalities and future risk of death.

ABSTRACT:

Background

The identification of novel predictors of poor outcome may help stratify cardiovascular risk. Aim was to evaluate the individual contribution of blood cell count parameters, as well as their clustering, on the risk of death and cardiovascular events over the long term in the population-based Malmö Diet and Cancer Study cohort.

Methods

In 30,447 individuals (age 57 ± 8 years), we assessed the incidence of all-cause death (primary endpoint) and major adverse cardiovascular events (MACE, secondary outcome measure) according to absence or presence of one, two and three factors at baseline out of the following: anaemia, leukocytosis and thrombocytosis. Median follow-up was 16 years.

Results

The percentages of all-cause death were 19.5% in individuals without fac

SUBMITTER: Patti G 

PROVIDER: S-EPMC8365677 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature